First-line treatment of hypertension: from monotherapy to fixed low-dose combination therapy
نویسندگان
چکیده
منابع مشابه
Rational approaches to the treatment of hypertension: drug therapy—monotherapy, combination, or fixed-dose combination?
Blood pressure (BP) control is inadequate worldwide. Many clinical trials suggest that BP is not satisfactorily controlled using monotherapy in most patients. Free drug or fixed-dose combinations are other therapeutic options. The advantages and disadvantages for different treatment approaches are discussed in this review.
متن کاملTreatment of Hypertension: Monotherapy or Combination Therapy Monotherapy In Hypertension
Is there a place for monotherapy? Yes, there is a place for monotherapy. According to the Seventh report of the Joint National Committee in 2003 (1) and the European guidelines from 2007 (2) and 2009 (3), the first step in hypertension control is changing lifestyle before initiating medical treatment. According to the baseline blood pressure and the presence or absence of target organ damage an...
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Hypertension is the leading cause of disability and cardiovascular mortality world-wide. Approximately one-third of the US adult population and over a billion people world-wide have hypertension. Despite increased awareness of hypertension and availability of many effective antihypertensive agents, only one third of patients achieve their target blood pressure (BP). All expert panels now recomm...
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Hypertension is a major risk factor for cardiovascular disease. Its prevalence is increasing worldwide, and is more common in low and middle-income countries. The effectiveness of hypertension treatment is determined by health cost, awareness, and patients' compliance with the treatment. People worldwide with an adequate control of hypertension correspond to a very small percentage in low and m...
متن کاملImproved persistence and adherence to diuretic fixed-dose combination therapy compared to diuretic monotherapy
BACKGROUND Diuretics are recommended as initial treatment for hypertension. Several studies have suggested suboptimal persistence and adherence to thiazide diuretic monotherapy; this study compared patient persistence and adherence with hydrochlorothiazide (HCTZ) monotherapy to fixed-dose combinations containing HCTZ. METHODS Patients with at least one prescription claim during 2001 to 2003 f...
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ژورنال
عنوان ژورنال: Journal of Human Hypertension
سال: 2001
ISSN: 0950-9240,1476-5527
DOI: 10.1038/sj.jhh.1001204